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NanoKnife or Irreversible Electroporation (IRE) consists of placing a number of electrodes into the prostate to surround the area of significant cancer.
Short pulses of electricity using very high voltage are passed between the electrodes. This causes micropores to occur in all cells, including the cancer cells, which lead to their death.
This occurs by the process of apoptosis or natural (programmed) cell death. This does not cause inflammation which the other heat-based focal therapies do. Only cancer cells are damaged. Damage to other structures such as the nerves, urethra and sphincter are minimized.
NanoKnife for Prostate Cancer If you have been recently diagnosed with prostate cancer confined to the prostate gland, the minimally invasive, Nanoknife Treatment could be suitable for you. There are several treatment options for patients with prostate cancer including surgery, radiation, focal therapy or surveillance.
Technology NanoKnife treatment is a form of Irreversible electroporation (IRE) Effectively destroys cancer cells without the use of thermal injury which minimizes injuries to normal prostate cells and nerves responsible for erections Induces apoptotic-like cell death resulting in complete ablation Precise and customizable ablation zones Immediate real-time visualization |
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The Procedure
The procedure is performed as an outpatient basis and you go home the same day. No admission to hospital is required.
You will be asleep and remain asleep until the procedure is complete
During the procedure, electrodes the size of a long thin needles will be directed inserted into the prostate gland through the skin underneath your scrotum using ultrasound and MRI guidance
The number of electrodes used can range from 2 to 6
Once the electrodes are placed, your physician will initiate a series of electrical pulses
After your physician has delivered a sufficient number of pulses to the targeted area, the procedure is complete, and the electrodes are removed
Is NanoKnife right for me?
NanoKnife irreversible electroporation (IRE) treatment is appropriate for most people with prostate cancer that is confined within the prostate gland. However, every case and patient are unique. One of our leading urologists will gladly provide you with a Prostate Cancer Assessment and determine whether NanoKnife is a suitable approach. We encourage you to contact us today to discuss the possibility of NanoKnife treatment for you.
Dr. Ravi Kumar completed his Bachelor of Health Sciences at McMaster University. He then pursued his Medical Doctorate and Urology residency at The University of Ottawa. He subsequently completed a fellowship in Urologic Oncology and Robotic Surgery at the Princess Margaret Cancer Centre at the University of Toronto. During his fellowship, he obtained a Master of Engineering from the Institute of Biomedical Engineering at the University of Toronto. He is the co-lead author of the Canadian Urological Association/American Urological Association guideline on the diagnosis and management of adrenal masses.
Dr. Kumar treats a wide variety of urologic conditions including BPH and kidney stones, with a special focus on delivering cutting-edge care for prostate cancer, kidney cancer and bladder cancer.
Dr. Ashwin Maharaj obtained his undergraduate degree in Biology/Physiology from the University of Western Ontario (BSc). e became certified through is a Diplomate of the American Board of Surgery and was certified as fellow of the American College of Surgeons (FACS) and recently recertified. He is a member of the Canadian Association of General Surgeons. His current clinical interests are devoted to outpatient acute and chronic gastrointestinal medicine/surgery as well as abdominal wall hernia surgery and practices in certified facilities in Toronto. He has research experience in gastrointestinal disease as well as surgical education teaching resident surgeons and medical students.
Dr. Diana Magee completed her undergraduate education at Cornell University followed by a Master of Public Health degree at Boston University. She received her medical degree from Queen’s University and completed her urology residency at the University of Toronto. While in residency she enrolled in the Surgeon Scientist program and completed her Master of Science in Health Services Research. She completed her fellowship in urologic oncology at Fox Chase Cancer Center in Philadelphia. Dr. Magee’s area of expertise is in the management of urologic cancers as well as performing minimally invasive surgery.
Dr. Pianezza completed his medical degree (MD) at the University of Ottawa in 2002. He became a member of the Royal College of Physicians of Canada (FRCSC). He then completed a one-year fellowship in minimally invasive surgery and endourology at the University of Alberta in Edmonton in 2008.
Dr. M. Pianezza has been a staff urologist in Sudbury at the Health Sciences North since January 2010. He was Head of Urology from February 2013 to September 2016. He is an Assistant Professor of Surgery at the Northern Ontario School of Medicine.
Dr. Heimrath completed his medical school at the University of Ottawa, his surgical residency at McGill University, and his Endourology, Minimally Invasive, and Robotics Fellowship at the University of Toronto. Dr. Heimrath’s areas of expertise include the management of complex kidney stones and urologic cancers as well as performing minimally invasive surgery. Since 2016, Dr. Heimrath has worked overseas in Malawi and Rwanda to explore opportunities to build urologic and surgical capacity in the developing world. He is a partner in the Urology Global Surgery initiative at the University of Toronto and holds a lecturer appointment with the University of Toronto.
Small intestinal bacterial overgrowth (SIBO) is a clinical condition characterized by a malabsorption syndrome due to an increase in microorganisms within the small intestine.
The Clinic at Beverly Hills offers patients the option between two industry leading gastric balloon procedures. The traditional endoscopy guided Orbera Gastric Balloon and the revolutionary swallowable Allurion Gastric Balloon.
Hemorrhoids are a natural part of the human body and, when healthy, assist with the closure of the anus.
Hemorrhoids are vascular cushions that move blood to and from the anus and help support the function of the sphincter. Most people think of hemorrhoids as the disorder known as hemorrhoids or piles.
Stress Urinary incontinence (SUI) means the uncontrollable loss of urine – an involuntary loss or leakage of urine during precipitating activities like coughing, laughing, sneezing, straining, exercising etc. Early signs of SUI are complaints relating to dysuria, frequency, and urgency. At TCBH Surgical Centre, we offer two treatment options for Stress Urinary Incontinence.
Benign prostatic hyperplasia (BPH) is a condition in which your prostate grows in size. Your prostate is a gland that rests below your bladder and in front of your rectum. It’s about the size of a walnut, and it surrounds part of your urethra. Your urethra is a tube that carries urine and sperm (ejaculate) out of your body. If your prostate grows in size, it can prevent urine and ejaculation from passing through your urethra. BPH is not cancerous. However, symptoms of BPH may indicate more serious conditions, including prostate cancer. TCBH Surgical Centre provides two treatment options.
How The Rezum™ Water Vapor Therapy Works
NanoKnife or Irreversible Electroporation (IRE) consists of placing a number of electrodes into the prostate to surround the area of significant cancer.
Short pulses of electricity using very high voltage are passed between the electrodes. This causes micropores to occur in all cells, including the cancer cells, which lead to their death.
Dr. Luke Fazio is the current Chief of Urology at Humber River Hospital. Dr. Fazio received his medical degree from McGill University in 1999. Following this, he finished his Endourology and Minimally Invasive fellowship at the University of Toronto. As the Urology Medical Director, he has brought many minimally invasive programs to TCBH and is working on future projects. He currently sits on numerous committees and is an advocate for innovation in healthcare. He is the physician lead for the Da Vinci Robotic Surgery Program. He also is the Chair of the Innovation Committee.
Dr. Bhargava has a primary focus of providing care for her patients in the form of minimally invasive procedures and cutting edge technology. She is the Medical Director of TCBH Surgical Centre (The Clinic at Beverly Hills Healthcare) and has been instrumental in bringing Laser Hemorrhoid Treatment to her Centre.
Achievements:
Dr. Bhargava completed both her medical school and surgical residency at the University of Western Ontario. In addition to her Bariatric fellowship, she has also completed Minimally Invasive fellowship at the University of Cincinnati in Ohio.
Dr. Bhargava has published multiple research papers and lead articles.
Memberships:
Canadian Medical Association, Canadian Association of General Surgeons, Society of American Gastrointestinal and Endoscopic Surgeons, Royal College of Physicians and Surgeons of Canada, College of Physicians and Surgeons of Ontario, and American Society of Bariatric Surgery